Raspberry Pi Pico's built-in bootloader allows you to write firmware via USB or SWD. However, in some situations, other interfaces may be useful. Picoboot3 now offers the options of UART, I2C and SPI.

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# the second serial port. If you check (for example by running mpremote connect # list) then you should now see two USB serial devices. # 4. Connect to one of the new ports: mpremote connect PORTNAME ...